Abstract

A model based upon minimization of surface energy is proposed as an explanation for compaction and internalization of cells during mammalian embryo development. The model is used to simulate and graphically display these phenomena on a computer. † Fulbright Scholar. On leave of absence from the Department of Biology, University of Chile, Casilla 653, Santiago, Chile. ‡ Visiting from: Cavendish Laboratory, Madingley Road, Cambridge CB3 0HE, England, Present address: La Jolla Institute, P.O. Box 1434, La Jolla, CA 92038, U.S.A.

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