Abstract

We developed a realistic model of a bipolar receptor cell of the olfactory epithelium. It has four compartments, namely cilia, dendritic knob, dendrite and soma. Cilia is a biochemical compartment including the molecular pathways of odor interpretation; dendrite is a passive compartment without channels; dendritic knob has Ca 2+-dependent chloride channels; and soma has all channels of Traub's CA3 hippocampal pyramidal neuron model plus Moczydlowski–Latorre's BK channel model. A pool of molecular odors, which increase Ca 2+ intracellular concentration and conductance of chloride channels, provides the input. The model's bursting behavior compares well with experimental data found in literature.

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