Abstract
Hyperthermia with a radiofrequency electric field can treat a cancer by delivering energy to heat and kill cancer cells. For a deeply located tumor, focused energy to raise its local temperature selectively is crucial for effective cancer treatment with minimal injury to normal tissues. We evaluated the selective heating characteristics of hyperthermia with 13.56 MHz radiofrequency energy in phantom models by experimental and computational approaches. Phantom materials with different electrical properties such as distilled water, normal saline, egg white and porcine meat were used. Temperature rise in depthwise during heating at 75 W output power was compared. The temperature of the egg white increased selectively in the distilled water but not significantly in the saline. Numerical simulation was performed using SEMCAD X software to calculate the distributions of specific absorption rate (SAR) and temperature, which enabled us to elucidate the selective heating mechanism in those phantom models.
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