Abstract
Simulating Cancer: Computational Models in Oncology
Highlights
The papers in this Special Topic span a broad spectrum of cancer cell-related subjects from intracellular modifications in individual cells to complex interactions between tumor cells and tumor microenvironments to emerging behaviors of cell populations on the organ and whole body scale
Various types of anticancer treatments have been discussed in this Special Topic, including chemotherapy, radiotherapy, immunotherapy, and differentiation therapy
Howk et al (3) use a single cell model of two-hit mutations of normal cells into endometrial cancer cells to predict the frequency of cancer stem cells in endometrial cancer
Summary
The papers in this Special Topic span a broad spectrum of cancer cell-related subjects from intracellular modifications in individual cells to complex interactions between tumor cells and tumor microenvironments to emerging behaviors of cell populations on the organ and whole body scale. This collection includes papers on brain, ovarian, and colon cancers, as well as on melanomas, leukemias, sarcomas, and head and neck tumors. Various types of anticancer treatments have been discussed in this Special Topic, including chemotherapy, radiotherapy, immunotherapy, and differentiation therapy.
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