Abstract
Synthesis of chemical compounds oftentimes produce a mixture of desired and undesired components. The ease of purification and recovery of the desired component more often than not determines the viability of the production technology. Simulated Moving Bed (SMB) technology is a continuous purification and separation technique with better performance (less solvent consumption and higher throughput) than traditional batch chromatography. SMB is a continuous separation technology which can be used to achieve the desired product purity with considerably lower power and raw material consumption. A lot of research and development is undergoing in the SMB technology which is enabling the search for more economical and carbon neutral ways of producing industrial chemicals. SMB has proven to be of great assistance in extracting products produced in biorefinery fermentation processes in an economical and energy efficient fashion. This chapter outlines the various processes the author has developed using SMB technology, its use in biorefineries, and prospective use in the future.
Highlights
Simulated Moving Bed (SMB) technology is an improvement over the traditional batch chromatography to a continuous chromatography process
SMB technology has only been used for binary separations i.e. two component or at most three components
Another adsorbent studied for the SMB process was silica bonded with C-18
Summary
Simulated Moving Bed (SMB) technology is an improvement over the traditional batch chromatography to a continuous chromatography process. SMB allows scaleup of lab chromatography process for high production outputs needed in the chemical industry. Most chemical reactions produce many byproducts along with the desired product. Many purification steps are needed in order to achieve the desired purity of the final product. Synthesis of products have traditionally been given more importance in the chemical industry. The recovery and purification of desired product is often more time consuming and costly in comparison to the synthesis reaction. Almost every chemical manufacturing operation requires the use of purification process to achieve the desired product purity. In this chapter the author focuses on use of SMB in the energy, pharmaceutical, and nutraceutical industry and how the use of this technology enables the development of greener and sustainable process
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