Simplifying Proton NMR Spectra by Instant Homonuclear Broadband Decoupling

N Helge Meyer,Klaus Zangger

doi:10.1002/anie.201300129

N Helge Meyer, Klaus Zangger

Open Access

https://doi.org/10.1002/anie.201300129

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Abstract

However, these techniques have not been widelyused, since they are insensitive and usually complicatedprocessing schemes have to be applied to achieve the desiredhomonuclear decoupling. Recently, the slice-selective broad-band-decoupling during a weak gradient field (also calledZangger–Sterk or ZS method)

Highlights

NMR spectroscopy is a versatile tool to determine structural, chemical, and physical properties of molecules
The slice-selective broadband-decoupling during a weak gradient field[14] has been rediscovered and improved to become a more general way to record pure shift spectra.[1, 7, 15]
The ZS-method employs the concept of slice-selective excitation by a weak magnetic gradient field to decouple all spins: Different parts of the NMR sample experience different magnetic field strengths when a linear gradient is applied

Summary

Introduction

NMR spectroscopy is a versatile tool to determine structural, chemical, and physical properties of molecules. The slice-selective broadband-decoupling during a weak gradient field ( called Zangger–Sterk or ZS method)[14] has been rediscovered and improved to become a more general way to record pure shift spectra.[1, 7, 15] Lupulsecu et al described the use of BIRD pulse trains during individual data acquisition blocks to achieve single-shot broadband decoupling of 1D 1H spectra and avoiding additional processing schemes.[16]

Results

Conclusion