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Abstract
This article describes the application of a simplified Bayesian method for estimation of doses from a mixed field using cytogenetic biological dosimetry, taking as an example neutron and gamma radiation emitted from the MARIA nuclear research reactor in Poland. The Bayesian approach is a good alternative to the commonly used iterative method, which allows separate dose estimation. In the present paper, a computer program, which uses the iterative and simplified Bayesian methods to calculate mixed radiation doses, is introduced.
Highlights
Cytogenetic biological dosimetry includes a group of methods based on assessing the frequency of biomarkers, such as dicentric chromosomes in human peripheral blood lymphocytes, to estimate radiation doses of those who have been exposed in occupational accidents or incidents (IAEA 2011).Dose estimation with the dicentric assay after accidental exposure to mixed, i.e., neutron and gamma radiation (n + γ) is more complex than estimation after exposure to a non-mixed field, because the human body is irradiated by a combination of two radiation types
The objective of this paper is to present the mentioned simplified Bayesian approach for dose estimation using the results of dicentric assay analysis after accidental overexposure to mixed n + γ radiation, which was implemented into a computer program, and to compare the results with those obtained by the full Bayesian method proposed by Brame and Groer (2003) and by the classical method (IAEA 2011, Słonecka et al 2018)
The program proposed in the present paper allows for calculation of separate doses of the components of a mixed radiation field composed of low- and high-LET radiation using a simplified Bayesian approach
Summary
Cytogenetic biological dosimetry includes a group of methods based on assessing the frequency of biomarkers, such as dicentric chromosomes in human peripheral blood lymphocytes, to estimate radiation doses of those who have been exposed in occupational accidents or incidents (IAEA 2011).Dose estimation with the dicentric assay after accidental exposure to mixed, i.e., neutron and gamma radiation (n + γ) is more complex than estimation after exposure to a non-mixed field, because the human body is irradiated by a combination of two (in general R) radiation types. Cytogenetic biological dosimetry includes a group of methods based on assessing the frequency of biomarkers, such as dicentric chromosomes in human peripheral blood lymphocytes, to estimate radiation doses of those who have been exposed in occupational accidents or incidents (IAEA 2011). It is shown here that this approach greatly simplifies the calculations and gives comparable results. The objective of this paper is to present the mentioned simplified Bayesian approach for dose estimation using the results of dicentric assay analysis after accidental overexposure to mixed n + γ radiation, which was implemented into a computer program, and to compare the results with those obtained by the full Bayesian method proposed by Brame and Groer (2003) and by the classical (iterative) method (IAEA 2011, Słonecka et al 2018). Besides the mixed doses calculation, the developed program gives the possibility of fitting curves to the data with the use of the robust Bayesian fitting (Fornalski et al 2010; Fornalski 2015; Fornalski and Dobrzyński 2015), which has been used to find the dose–effect calibration curves and its parameters
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