Simple Synthesis of Conjugated All-(E)-Polyenic Aldehydes, Ketones, and Esters Using Chemoselective Cross-Metathesis and an Iterative Sequence of Reactions: Application to the Synthesis of Navenone B

Abstract

By using a very simple sequence of reactions such as allylation, acetylation, chemoselective cross-metathesis, and elimination, even and odd conjugated all-(E)-polyenes can be synthesized from very simple alkenes.