Abstract
Simple silver salts and dicationic palladium bis(N-heterocyclic carbene) complexes were found to be effective and complementary catalysts for Nazarov cyclizations of divinyl β-keto esters. A sterically hindered palladium bis(NHC) catalyst provided remarkable endo:exo selectivity in cyclizations of cyclohexenyl β-keto esters, whereas AgSbF6 gave improved yields with electron-deficient substrates. The high activities observed with silver salts are significant, given their widespread use as additives in catalytic Nazarov reactions.
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