Abstract
Seven patients treated with anterior callosotomy for drug-resistant atonic seizures were tested to evaluate their simple reaction times (SRTs) to lateralized flashes before surgery (time 0) and then 15 (time I) and 90–100 days (time II) after the operation. The SRTs obtained at the three checkpoints were compared by means of ANOVA for the main effects of time, hand, and visual hemifield, and for their interactions. The mean number of omissions was also analyzed. The results showed increased SRTs at the first check after surgery, with a greater increase for the left hand, followed by a decrease close to the presurgical values. No difference between crossed and uncrossed conditions were observed; no differences in the omission rate were seen at postoperative evaluations. Finally, the left-hand performance showed a trend toward longer SRTs than the right-hand performance at all observations. Our data suggest that SRTs are only transiently affected by anterior callosotomy and that the side effects of surgery are greater in the left hand.
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