Abstract

Abstract Recently, the biggest challenge in agriculture is the search for new, effective, and ecological methods of protecting plants against diseases. One of the fastest-growing and prospective strategies is a method based on activating the plant’s natural defenses. The use of suitable substances (elicitors) stimulates the immune system of plants, which makes them resistant to infections even before the first symptoms appear. This article presents preparation, characterization, phytotoxicity, and plant resistance induction efficacy of 28 ester derivatives of nicotinic, isonicotinic, and 2,6-dichloroisonicotinic acids as potential inducers of plants’ natural immune system. Plant resistance induction efficacy tests were performed on tobacco Nicotiana tabacum var. Xanthi infected by the tobacco mosaic virus (TMV).

Highlights

  • Recently, the biggest challenge in agriculture is the search for new, effective, and ecological methods of protecting plants against diseases

  • We have successfully investigated the biological efficacy of 28 ester derivatives of nicotinic (1a–1j), isonicotinic (2a–2j), and 2,6-dichloroisonicotinic acid (3a–3f, 3i, 3j) where three derivatives (3f, 3i, 3j) were newly synthesized and characterized for the purpose of this article (Figure 1)

  • Compound 3g was not obtained due to steric hindrance caused by the presence of halogens attached directly to the heterocycle, and 3h was obtained with monoester derivative as an inseparable mixture

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Summary

Introduction

Abstract: Recently, the biggest challenge in agriculture is the search for new, effective, and ecological methods of protecting plants against diseases. One of the fastestgrowing and prospective strategies is a method based on activating the plant’s natural defenses. The use of suitable substances (elicitors) stimulates the immune system of plants, which makes them resistant to infections even before the first symptoms appear. This article presents preparation, characterization, phytotoxicity, and plant resistance induction efficacy of 28 ester derivatives of nicotinic, isonicotinic, and 2,6-dichloroisonicotinic acids as potential inducers of plants’ natural immune system. Plant resistance induction efficacy tests were performed on tobacco Nicotiana tabacum var. Xanthi infected by the tobacco mosaic virus (TMV)

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