Simple Diastereoselective Synthesis of (2S*,2′R*,3′R*,4S*)-2,3′-Diphenylspiro[chroman-3,2′-oxiran]-4-ols and (2S*,2′S*,3′S*,4S*)-2,3′-Diphenylspiro[chroman-3,2′-oxiran]-4-ols

Abstract

Oxiranes (epoxides) are very versatile building blocks in organic synthesis, and they can be opened up with a wide range of nucleophiles.1–3 Nucleophilic addition to epoxides plays a pivotal role i...