Similarity of Drug Names

Abstract

To the Editor.— Isosorbide is a new hyperosmotic agent that has recently been introduced in the United States for the short-term reduction of intraocular pressure. Another compound, isosorbide dinitrate, has been used in this country by internists for many years for the treatment of angina pectoris. The similarity between the generic names of the two compounds presents a potential for confusion. Because the hyperosmotic, isosorbide, is supplied only as a liquid, while isosorbide dinitrate is a tablet, perhaps this confusion will be minimized. Nevertheless, with the increasing trend toward the use of generic names, the internist and ophthalmologist should be aware of the potential problems, which might be lessened by the use of the full generic or brand name.