Abstract
Singletons born after fresh embryo transfer (ET) are associated with higher rates of preterm birth and low birthweight, while frozen embryo transfers (FET) seem to convey a higher risk of large for gestational age. However, studies comparing these outcomes using autologous oocytes are unable to adequately disentangle the potential effect of embryo vitrification from the possible consequences on endometrial receptivity caused by ovarian stimulation/preparation, prior to ET. Hence, the oocyte donation (OD) model is optimal for this differentiation and, so far, information available regarding neonatal outcomes is limited to either small and/or heterogeneous studies.
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