Silver-Catalyzed Carboxylation Reaction Using Carbon Dioxide as Carboxylative Reagent

Abstract

The transformation of carbon dioxide into value-added fine chemicals via homogeneous catalysis has gained much attention since carbon dioxide is an abundant, nontoxic, and inexpensive C1 feedstock. Silver catalysis has emerged as important synthetic methods for a wide range of organic transformations in the last two decades. In silver-catalyzed carboxylation reactions using carbon dioxide as a carboxylative reagent, silver(I) salts or complexes generally serve as a π-Lewis acid catalyst to activate unsaturated systems, especially alkynes, or in situ generate silver acetylides or arylsilver intermediates as reactive carbon nucleophiles. In this chapter, silver-catalyzed cyclization reactions of propargylic alcohols or amines, o-alkynylanilines, and alkynyl ketones with carbon dioxide are reviewed. Also, silver-catalyzed carboxylation of terminal alkynes and arylboronic esters with carbon dioxide is documented.