Silver Nanoparticles Biosynthesis Using White Nest-Swiftlet Extract: A Sustainable Pathway for Nanomedicine Applications

Abstract

Demand of antibacterial-based metal nanoparticles biomaterials against broad ranges of pathogenic microorganisms show unique functionality in a wide range of applications. Silver nanoparticles (AgNPs) play a major role especially in nanomedicine field; thus, there are urge to find more economic and eco-friendly synthesis method without harming the consumers and/or patients. In this study, an aqueous of white nest-swiftlet (Aerodramus fuciphagus) extract was used as bio-reductant and stabilizing agent to synthesis the AgNPs. The changes colour from colourless to reddish brown within 15 minutes under heat condition, 50 mM AgNO3 concentration and 3, 4, and 5 % (w/v) edible bird nest (EBN) dose indicated the successful of AgNPs biosynthesis by using visual indication. Further characterization of AgNPs was carried out by UV-visible spectroscopy through presence of plasmon resonance band between 410 nm to 430 nm. Infrared spectroscopy technique was used to analyse the involvement of biomolecules in EBN reduced the AgNPs. Their morphology and particle size analysed by field emission scanning electron microscopy (FESEM) showed nearly spherical in size with average diameter of 35 nm. Energy dispersive X-ray (EDX) attached with FESEM evaluate the composition of silver in the solutions. The content of silver increasing with the concentration of EBN extract. On the basis of results and facts, the green approach on AgNPs synthesis through EBN can be proposed as ecologically and economically feasible approach to become antibacterial wound dressing.