Abstract
The synthesis and characterization of poly (amido amine) dendrimer/DNA nanogel containing silver nanoparticle have been reported. Initially dendrimer protected-nanoscale silver particles have been synthesized in aqueous medium. UV-Vis spectra and transmission electron micrograph indicate almost spherical silver particles with an average diameter 6 ± 2 nm were formed. The preformed dendrimer protected silver nanoparticle solution was mixed with DNA solution to fabricate the dendrimer/DNA complex. At the dendrimer/DNA-mixing ratio (number ratio of NH 2 groups in dendrimer vs phosphate groups in DNA) 0.3, aggregates (nanogel) were formed. Transmission micrograph revealed the presence of silver nanoparticles inside that gel matrix. Binding of dendrimer molecule with DNA chain occurs through electrostatic interaction. This kind of approach promises the development of polyelectrolyte-based soluble conductive nanowires and three dimensionally self-assembled complex nanostructure.
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Schedule a callMore From: Zenodo (CERN European Organization for Nuclear Research)
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