Abstract

Silica based silver doped nanobioactive glass compositions (58SiO2−33CaO−9P2O5 and 58SiO2−23CaO−9P2O5−10Ag2O(mol%)) were synthesized by a simple sol–gel route. The prepared samples were comprehensively characterised by X-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy and scanning electron microscopic studies. The results reveal that the prepared samples have amorphous phase with spherical morphology and having a particle size less than 100 nm. The specific surface areas were 90 and 61 m2g−1 respectively. The in vitro bioactivity of glass samples were confirmed by the formation of hydroxyapatite layer on glass surfaces. The Ag2O-doped nanobioactive glasse samples shows reveal significant antibacterial activity compare with base glasses.

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