Abstract
ABSTRACTThe ordered microstructure of the corneal stroma determines the transparency of the cornea. The difficulty of constructing three‐dimensional corneal tissue mainly lies in the reconstruction of the corneal stroma. This article reports propionamide/silk fibroin composite membrane materials for use in corneal regeneration. X‐ray diffraction is used to explore the structure of the composite fibroin membrane. Propionamide acts as a crosslinking agent and inhibits the formation of larger crystal grains controlling the crystallization process. Corneal stromal cells are seeded on sterilized composite films. Propionamide/fibroin membranes with different blending proportions exhibit stable transparency and good cell compatibility. The results demonstrate that composite fibroin membranes are suitable potential materials for use in corneal stromal cell proliferation and repair. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 42407.
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