Abstract
Purpose: Physical stress and tear film interaction are likely factors for contact lens discomfort. Bioactive lipid mediators (LM) that are generated from ω-3 and ω-6 polyunsaturated fatty acids (PUFA) regulate ocular surface physiology and pathophysiology, are constituents of human tears and potential biomarkers. Whether silicone hydrogel lenses interact with tear LM and PUFA was investigated.
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