Silica-supported perchloric acid (HClO4/SiO2) as efficient catalyst for the synthesis of tetraazamacrocyclic complexes of transition metals

Abstract

Silica-supported perchloric acid (HClO4/SiO2) was used to catalyze the synthesis of tetraazamacrocyclic complexes of Co(II), Ni(II), Cu(II), and Zn(II) from the corresponding metal chlorides, nitrates, or acetates, isatin, and benzene-1,2-diamine in ethanol. The use of HClO4/SiO2 as catalyst allowed the reaction to be performed under stirring at room temperature instead of traditional reflux and completed in two hours. The synthesized complexes were characterized by molar conductance and magnetic susceptibility measurements, IR, electronic, 1H NMR, and mass spectra, and thermogravimetric and X-ray powder analyses. On the basis of these data, six-coordinate octahedral geometry was proposed for all complexes. The synthesized complexes were also tested for antimicrobial activity.