Abstract
There are some patients with asthma who have a good response to standard therapy, but there are always some whose symptoms are not well controlled despite treatment with standard asthma medications. Guidelines for the treatment of asthma recommend that patients who have asthma that is difficult to control be evaluated for the presence of coexisting conditions such as gastroesophageal reflux, obesity, obstructive sleep apnea, rhinitis or sinusitis, and chronic stress or depression, since these conditions could be contributing to the lack of response to therapy. Previously published controlled trials have suggested that treatment with a proton-pump inhibitor alleviates asthma that . . .
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