Abstract

Risperidone, which is one of the most commonly prescribed second-generation antipsychotics can cause several sexual adverse effects. To date, research on the sexual side effects of risperidone has ...

Highlights

  • Risperidone is one of the most widely used secondgeneration antipsychotics in clinical practice

  • Research on the sexual side effects of risperidone has been mostly restricted to symptoms of decreased libido, erectile dysfunction and delayed ejaculation and far too little attention has been paid to risperidone associated retrograde ejaculation

  • Overall the treatment plan was effective and tolerable for the patient during the 6-month follow-up period. This is the first report on the use of structured treatment interruptions for the management of risperidoneinduced retrograde ejaculation

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Summary

Introduction

Risperidone is one of the most widely used secondgeneration antipsychotics in clinical practice. Few studies have reported the occurrence of retrograde ejaculation associated with risperidone use resulting in a negative effect on treatment compliance [4,5,6]. The question is whether concurrent use of opiates and risperidone can increase the risk of retrograde ejaculation due to their anticholinergic and antiadrenergic effects.

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