SIGNIFICANCE OF RED CELL DISTRIBUTION WIDTH (RDW) AND NEUTROPHIL LYMPHOCYTE RATIO [NLR] IN ACUTE PANCREATITIS IN ASSESSING PROGNOSIS

Abstract

Background- Acute pancreatitis is a potentially lethal acute inammatory process with a highly variable clinical course. Extreme form of the disease can develop in 25% of patients and with an estimated mortality of 40%.Methods- This study aimed to evaluate the effectiveness of RDW & NLR in suspecting the outcome in patients with acute pancreatitis. It was carried out among 50 patients who had acute pancreatitis and were diagnosed based on diagnostic criteria for acute pancreatitis. RDW, WBC count, platelet count, RBC count, haemoglobin level, MCV, Serum Amylase, lipase, serum creatinine, total protein, albumin, total bilirubin, calcium, glucose, LDH, SGOT and SGPT levels and Ultrasound abdomen were done. NLR & RDW were done on days 0 & 2, and is correlated with the severity Out of 50 study subjects ,78% of the subjects were Resultsclassied as mild acute pancreatitis group and 22% as severe acute pancreatitis group. There is signicant change in RDW in severe acute pancreatitis group. NLR showed signicant change in mild and severe acute pancreatitis. The change in value is more signicant in 0 & 48 hrs in severe acute pancreatitis group. Also, NLR has more signicant rise during admission than at 48 hours. RDW & NLR values along Conclusionwith various scoring systems will be helpful for accurately predicting the severity of acute pancreatitis