Abstract
Capnocytophaga canimorsus can infect humans, mainly through animal bites, and cause sepsis. The Guillain-Barré Syndrome (GBS) due to C. canimorsus infection has not been reported in the past.A 51-year-old man developed distal dominant muscle weakness and severely decreased deep tendon reflexes in all four limbs after recovering from C. canimorsus sepsis. A nerve conduction study suggested acute motor axonal neuropathy. The patient was diagnosed with GBS and treated with intravenous immunoglobulin with good prognosis. Multiple anti-ganglioside IgM antibodies were found to be positive in the acute phase, but they showed immunoglobulin class-switch to IgG in the recovery phase.Clinicians should be aware of the possibility of GBS, especially acute motor axonal neuropathy, developing after C. canimorsus infection. Multiple anti-ganglioside IgM antibodies could be involved in the immunopathological mechanism of GBS after C. canimorsus infection, but additional studies should be done to understand the precise mechanism.
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