Abstract

Long noncoding RNAs (lncRNAs) are a heterogeneous class of RNAs with generally longer than 200 nucleotides. It has been proposed that LncRNAs as a piece of paracrine action would control cellular pluripotency, differentiation, maintenance and regulate tissue development, organogenesis and regeneration. Next generation sequencing (RNA-seq) has produced huge data about lncRNAs expression profile in different cell types and condition, but understanding the roles and functions of these novel lncRNAs is poorly understood.

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