Abstract
The purpose of this study was to evaluate the significance of liver volumetry as a parameter for hepatic functional reserve in cirrhotic patients with hepatocellular carcinoma. Liver volume was calculated from preoperative computed tomograms of 44 cirrhotic patients who underwent elective hepatic resections for hepatocellular carcinoma. The liver volume per body weight of non-alcoholic cirrhotics was significantly smaller than that of alcoholic cirrhotics (20.9 vs. 26.7 cc/kg; p=0.03). The values for alcoholic cirrhotics was comparable with normal values. The liver volume per body weight of the cirrhotic patients demonstrated correlation with the preoperative serum albumin (p<0.01) and indocyanine green clearance (p=0.02). We conclude that the determination of hepatic atrophy by volume try can serve as a parameter for the assessment of hepatic reserve but not as a predictor of postoperative complications in elective liver surgery for cirrhotic patients.
Highlights
Liver cirrhosis used to be considered a contraindication to hepatic resection, carefully selected cirrhotic patients can undergo elective hepatic resection safely [1,2,3]
This study demonstrated a significant difference in the liver size by the etiology of liver diseases..To date, little is known about the relationship between the etiology of liver diseases and hepatic atrophy
Hendersonet al. in 1983 [10] reported hemodynamic differences between alcoholic and nonalcoholic cirrhotics after distal splenorenal shunt, in which the mean liver size calculated by computed tomography (CT) tended to be, but was notsignificantly smaller in eight non-alcoholic cirrhotics as compared to 16 alcoholic cirrhotics (1A89 vs. 2,113 cc)
Summary
The purpose of this study was to evaluate the significance of liver volumetry as a parameter for hepatic functional reserve in cirrhotic patients with hepatocellular carcinoma. Liver volume was calculated from preoperative computed tomograms of 44 cirrhotic patients who underwent elective hepatic resections for hepatocellular carcinoma. The liver volume per body weight of,non-alcoholic cirrhotics was significantly smaller than that of alcoholic cirrhotics (20.9 vs 26.7 cc/kg; p=0.03). The values for alcoholic cirrhotics was comparable with normal values. The liver volume per body weight of the cirrhotic patients demonstrated correlation with the preoperative serum albumin (p
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