Abstract
Researchers at University of Fukui, Japan analyzed the relation between EEG abnormalities and PDD or ADHD, and assessed the clinical utility of EEG in the differential diagnosis of these disorders.
Highlights
Researchers at University of Fukui, Japan analyzed the relation between EEG abnormalities and PDD or ADHD, and assessed the clinical utility of EEG in the differential diagnosis of these disorders
No significant differences in the laterality of paroxysmal discharges were found between PDD and ADHD
Patients classified as inattentive subtype ADD showed no EEG abnormality
Summary
Pharmacologists at Georgetown University, Washington, DC examined functional synaptic maturation in striatal medium spiny neurons from neonatal rats exposed to antiepileptic drugs (AED) with proapoptotic action (phenobarbital, phenytoin, lamotrigine) and without proapoptotic action (levetiracetam). Researchers at University of Fukui, Japan analyzed the relation between EEG abnormalities and PDD or ADHD, and assessed the clinical utility of EEG in the differential diagnosis of these disorders. The study involved 64 PDD children and 22 ADHD children with no history of epilepsy or progressive neurological or psychiatric disease. Paroxysmal discharges at the frontopolar-frontal brain regions and background EEG abnormalities were detected preferentially in the PDD group expressing persistence or hypersensitivity, whereas central-temporal discharges were detected preferentially in the ADHD group expressing impulsivity.
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