Abstract
Cathodic photoelectrochemical (PEC) bioassay is more resistant to reductive interferents, and development of high-performance photocathode is imperatively required in precise monitoring target in complex matrices. In this work, a plasmonic Au activated amorphous MoSx photocathode (a-MoSx/Au) was fabricated by sequential electrodeposition. Coupled with a sensitization amplification strategy induced by target-aptamer recognition, an ultrasensitive and high-affinitive signal-on cathodic PEC aptasensor for insulin detection was developed. Under optimum conditions, the sensor exhibits a wide linear range (0.1 pg/mL~100 ng/mL) and an ultralow detection limit (28 fg/mL) even lower than most sensors reported so far. Plasmonic Au activation and target-induced sensitization effect are responsible for high-performance PEC aptasensing of insulin at a-MoSx photocathode.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.