Abstract

Aim: Stevens Johnson Syndrome and Toxic Epidermal Necrolysis (SJS/TEN) is a life-threatening mucocutaneous skin reaction that usually develops against drugs, although there are various factors in its etiology. In this case report, SJS due to antiepileptic drug use will be briefly reviewed. Case:20-year-old female patient was seen in the emergency department with a generalized tonic-clonic seizure. With the detailed anamnesis and laboratory findings obtained, the patient was started lamothyrigine therapy. While the dose was titrated in the treatment, treatment was stopped in the patient who developed SJS, and a new antiepileptic drug was started. Conclusion: SJS/TEN is the same disease spectrum with different severity. They are classified according to the percentage of skin detachment area. The pathogenesis of SJS/TEN is still unclear and optimal treatment options are still controversial.

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