Abstract
been called has been reported in Michigan and California. It was first thought to be an active form of anemia, but subsequent accounts seem to indicate that it generally exists in a latent form. Sickle-cell anemia in humans was first reported by Herrick (1). It was described as a hereditary and familial disease present and recognizable in very early infancy, and peculiar to the negro race. It was thought that there is some congenital defect of the red corpuscles which renders them more susceptible to hemolytic toxins and to phagocytosis. The red cells, however, show normal resistance, and in some cases increased resistance, to hypotonic salt solutions. O'Roke (2) reported 14 sickle-cell cases in 178 white-tailed deer examined
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