Abstract
Sickle cell disease and COVID-19: Atypical presentations and favorable outcomes.
Highlights
COVID-19 pandemic has already claimed several lives
Our first patient is a young woman with SS Bantu phenotype, aged 23, who came for a regular visit for planning her exchange transfusion (ET)
The third patient is a 23-year-old lady with SS sickle cell disease (SCD) admitted for vaso-occlusive crises (VOC) that developed after repeated bouts of vomiting and developed acute renal insufficiency
Summary
COVID-19 pandemic has already claimed several lives. Individuals with underlying health conditions including sickle cell disease (SCD) are considered to be at higher risk of complications from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While the control chest CT scanner on day 9 showed no more pneumomediastinum and no lung embolism or infiltrate, she developed a focal non occlusive deep venous thrombosis (DVT) on femoralis comunis vena at the site of catheter insertion at day 11 (despite thrombo-prophylaxis with low dose enoxaparin). Her chest scan showed bi-basal lung lesions atypical for COVID, which could be interpreted as a delayed hemolytic transfusion reaction (DHTR).
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