Abstract

Sialolipoma is a histologic variant of lipoma characterized by proliferation of mature adipocytes with secondary entrapment of normal salivary gland tissue. These tumors occur mainly in the parotid gland and palate of female adults. Herein, we report a rare case of a sialolipoma in a 42-year-old male patient, presenting as a painless yellowish nodular lesion of soft consistency on the border of the tongue. A provisional diagnosis of lipoma was established, and an excisional biopsy was performed. Histopathologic analysis revealed a proliferation of mature adipocytes in a lobular arrangement with secondary entrapment of normal salivary gland tissue. The diagnosis was sialolipoma. The patient remains with no evidence of recurrence at 5-month follow-up. Pathologists must recognize sialolipomas to avoid misdiagnoses with other lipomatous tumors that can affect salivary glands.

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