Abstract
Synthesis of 5R-Acetamido-4S-amino-4H-pyran-6R-O-(1-ethyl)propyl and 6R-(1-oxo-2-ethyl)butyl 2-carboxylic acids ( 4 and 5) and their evaluation as inhibitors of influenza virus sialidase is described. Both compounds showed good inhibitory activity with marked selectivity for influenza A sialidase.
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