Abstract
Sialic acid levels were determined in cervical mucin from women not using contraceptive protection (controls), women using Copper Seven IUD containing 200 mm 2 of copper wire, and women using an inert Dalkon Shield IUD. The sialic acid levels of the control cervical mucin were found to undergo cyclic variation during the menstrual cycle with higher levels in the preovulatory phase than in the luteal phase. There was no significant difference in sialic acid levels of cervical mucin between the preovulatory and luteal phase of the contraceptive regimes, or when compared to the controls. Removal of sialic acid by neuraminidase from late preovulatory cervical mucin resulted in a structure similar to that found in the early preovulatory and luteal phase when examined by scanning electronmicroscopy.
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