Abstract

Sialadenoma papilliferum (SP) is a rare, benign neoplasm of salivary gland origin, which manifests as a painless, exophytic, papillary lesion, accounting for less than 1% of the minor salivary gland tumors. About 70% of the reported cases have occurred in the minor salivary gland of the palate, in middle-aged or older male patients. The present report aims to describe an unusual case of SP of the lower lip that mimicked a mucocele, in a 20-year-old woman. The clinical examination showed a nodular growth, measuring 3 × 1 cm, sessile, smooth-blue surfaced, slightly tender, with undetermined etiology. An excisional biopsy was performed and the histopathological examination revealed an exophytic papillary proliferation composed of well-differentiated stratified squamous epithelium, which merged with a glandular proliferation occupying the submucosa. Based on the clinical and histopathological findings, the final diagnosis was SP. Seven months of follow-up showed no recurrence.

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