Abstract
Background The basophil activation test (BAT) is an in vitro test which allows to identify children with food allergies at the sensitization stage and clinical manifestations of atopic dermatitis\\eczema (AD). The aim of our study was to observe the BAT in children with food allergies, optimize the diagnosis compared with other tests, and select an elimination diet. Early detection of sensitization and elimination of causative allergens can help prevent the progression of the disease into bronchial asthma in such children.
Highlights
The basophil activation test (BAT) is an in vitro test which allows to identify children with food allergies at the sensitization stage and clinical manifestations of atopic dermatitis\\eczema (AD)
We investigated 89 children from 3 months to 12 years with FA experience and AD symptoms in varying severity
The level of spontaneous activation of basophils (SAB) it means basic expression of basophiles, depended on the severity of AD (p
Summary
The basophil activation test (BAT) is an in vitro test which allows to identify children with food allergies at the sensitization stage and clinical manifestations of atopic dermatitis\\eczema (AD). The aim of our study was to observe the BAT in children with food allergies, optimize the diagnosis compared with other tests, and select an elimination diet. Detection of sensitization and elimination of causative allergens can help prevent the progression of the disease into bronchial asthma in such children. Instead, it best used with other complementary tests for the clearest representation of each condition. The BAT should be recommended to help prescribe elimination diets for patients with FA. Authors’ details 1Sankt-Petersburg State Medical Pediatric University, St Petersburg, Russia. Authors’ details 1Sankt-Petersburg State Medical Pediatric University, St Petersburg, Russia. 2Nikiforov Russian Center of Emergency and Radiation Medicine, St Petersburg, Russia
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