Abstract
The pulse pressure is the difference between the systolic and diastolic blood pressure. It is influenced by the stroke volume and vascular resistance. As people age the walls of their arteries become stiffer. This increases the pulse pressure. A high pulse pressure may be associated with reduced coronary perfusion. It may therefore be a predictor of future cardiovascular events, but this has not been confirmed by meta-analysis. There are no drugs specifically aimed at reducing arterial stiffness. Treatment should be aimed at systolic and diastolic pressure rather than reducing pulse pressure.
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