Abstract

Preimplantation genetic testing for aneuploidy (PGT-A) is widely used in IVF and aims to improve outcomes by avoiding aneuploid embryo transfers. Unlike other PGT-A methods, PGT-A analyzed using next generation sequencing (NGS) make it possible to identify mixes of aneuploid and euploid cells in trophectoderm biopsies. In such instances the source embryos are classified as mosaic. Also, some IVF clinics are routinely transferring embryos diagnosed through PGT-A as mosaic anueploid with greater frequency to patients who lack available euploid embryos.

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