Abstract
The management of atrial fibrillation in patients with heart failure (HF) has been an on-going challenge, with no clear evidence for a rhythm control strategy until recent clinical trials using catheter ablation. Recently, the RAFT-AF study (randomized ablation-based rhythm-control versus rate-control trial in patients with heart failure and atrial fibrillation; ClinicalTrials.gov identifier: NCT01420393) was published suggesting benefit for atrial fibrillation ablation in patients with HF with reduced ejection fraction. The data from this pivotal trial are reviewed and placed into context with other important trials. Taken together, these studies make a strong argument for considering catheter ablation for patients with HF and reduced but not preserved ejection fraction.
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