Abstract
Should acyclovir prophylaxis be used in late pregnancy in women with recurrent genital herpes infection? How to use a clinical decision analysis.
Highlights
The purpose of this article is to explore the benefits of using decision analysis in clinical decision making when the published evidence about the effectiveness of an intervention is uncertain
Women with genital herpes infection in pregnancy are at risk of transmitting herpes to their baby at the time of delivery resulting in neonatal herpes infection
If there is evidence of an active recurrence delivery by caesarean section is recommended to avoid the risk of mother to child transmission.[5]
Summary
The purpose of this article is to explore the benefits of using decision analysis in clinical decision making when the published evidence about the effectiveness of an intervention is uncertain. The use of decision analysis will be explored using the example of aciclovir prophylaxis in late pregnancy for women with recurrent genital herpes infection.' The article draws on the guidelines published by Richardson and others which set out a framework for evaluating the usefulness of a clinical decision analysis model (table 1).[2 3]
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