Abstract

Otitis media, a common disease marked by the presence of fluid within the middle ear space, imparts a significant global health and economic burden. Identifying an effusion through the tympanic membrane is critical to diagnostic success but remains challenging due to the inherent limitations of visible light otoscopy and user interpretation. Here we describe a powerful diagnostic approach to otitis media utilizing advancements in otoscopy and machine learning. We developed an otoscope that visualizes middle ear structures and fluid in the shortwave infrared region, holding several advantages over traditional approaches. Images were captured in vivo and then processed by a novel machine learning based algorithm. The model predicts the presence of effusions with greater accuracy than current techniques, offering specificity and sensitivity over 90%. This platform has the potential to reduce costs and resources associated with otitis media, especially as improvements are made in shortwave imaging and machine learning.

Highlights

  • Otitis media, a common disease marked by the presence of fluid within the middle ear space, imparts a significant global health and economic burden

  • Otitis media refers to inflammation of the middle ear and encompasses a spectrum of pathology ranging from acute otitis media (AOM) and otitis media with effusion (OME) to chronic suppurative otitis m­ edia[1]

  • A total of 30 patients were recruited for the study. 23 of these patients had OME; 7 had RAOM

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Summary

Introduction

A common disease marked by the presence of fluid within the middle ear space, imparts a significant global health and economic burden. The model predicts the presence of effusions with greater accuracy than current techniques, offering specificity and sensitivity over 90%. This platform has the potential to reduce costs and resources associated with otitis media, especially as improvements are made in shortwave imaging and machine learning. The presence of an effusion in the middle ear, which is a sterile fluid collection in the setting of OME, as opposed to an acute infection in AOM, is characteristic to both of these c­ onditions[3].

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