Abstract

To compare visual acuity (VA), contrast sensitivity, stereopsis, and subjective visual performance of Acuvue® Oasys® for Presbyopia (AOP), Air Optix® Aqua Multifocal (AOMF), and Air Optix® Aqua Single Vision (AOSV) lenses in patients with presbyopia. A single-blinded crossover trial was conducted. Twenty patients with mild presbyopia (add ≤+1.25 D) and 22 with moderate/severe presbyopia (add ≥+1.50 D) who wore lenses bilaterally for 1 h, with a minimum overnight washout period between the use of each lens. Measurements included high- and low-contrast visual acuity (HCVA and LCVA, respectively) at a distance, contrast sensitivity (CS) at a distance, HCVA at intermediate (70 cm) and near (50 cm & 40 cm) distances, stereopsis, and subjective questionnaires regarding vision clarity, ghosting, overall vision satisfaction, and comfort. The test variables were compared among the lens types using repeated-measures ANOVA. Distance variables (HCVA, LCVA, and CS) were significantly worse with multifocal lens than with AOSV lens (p≤0.008), except for AOMF lens in the mild presbyopia group in which no significant difference was observed (p>0.05). Multifocal lenses had significantly greater HCVA at 40 cm than AOSV lens (p≤0.026). AOMF lens had greater intermediate HCVA than AOP lens (p<0.03). AOP lens demonstrated greater improvements in stereopsis than AOMF and AOSV lens in the moderate/severe presbyopia group (p≤0.03). Few significant differences in subjective variables were observed, with no significant difference in the overall vision satisfaction observed between lens types (p>0.05). The proportions of patients willing to buy AOSV, AOMF, and AOP lenses were 20%, 40%, and 50%, respectively, in the mild presbyopia group and 14%, 32%, and 23%, respectively, in the moderate/severe presbyopia group; however, these differences were not statistically significant (p≥0.159). Further development of multifocal lenses is required before significant advantages of multifocal lenses over single vision lens are observed in patients with presbyopia.

Highlights

  • More than one third of the world’s population is over 40 years[1] and is the age at which presbyopia generally begins developing

  • AOSV lens was significantly better than Acuvue® Oasys® for Presbyopia (AOP) lens for all distance variables (p≤0.007), with no statistically significant difference observed compared with AOMF lens (p≥0.213) or between the two multifocal designs (p≥0.115)

  • AOMF lens had significantly higher HCVA values compared with AOP lens (p=0.012), with no significant differences were observed between AOSV lens and either of the multifocal lenses (p≥0.058)

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Summary

Introduction

More than one third of the world’s population is over 40 years[1] and is the age at which presbyopia generally begins developing. Pres­byopia is an age-related condition that causes the eye to progressively lose its ability to focus on near objects. The correction of presbyopia traditionally involves either multifocal or separate reading spectacles; there has been considerable interest in using contact lenses because of their suitability for sports, cosmetic appeal, or a patient’s dislike for spectacles. Concurrent with an aging global population, the prevalence of presbyopia is estimated to increase from 1.2 billion in 2010 to 1.8 billion in 2050(2). The age of the average contact lens wearer is increasing, revealing a growing market for presbyopic contact lenses[3]. In an international survey conducted in 2011, Morgan et al reported

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