Short‐term in vivo morphologic changes of amniotic membrane after fibrin glue‐assisted pterygium surgery on anterior segment optical coherence tomography: a case series

Abstract

PurposeThe evaluations of morphologic changes of amniotic membrane (AM), even after successful AM transplantation surgery without complications, may be difficult. Moreover, there was no report regarding morphologic changes after fibrin glueassisted AM transplantation with pterygium excision. Here, we highlight and describe the use of spectral domain optical coherence tomography (OCT) for the evaluation of the morphologic features of amniotic membrane (AM) and of associated in vivo structural changes after fibrin glue‐assisted pterygium surgery.MethodsRetrospective Case Series.ResultsAll three patients underwent cryo‐preserved AM transplantation using the permanent inlay technique (epithelial side up) with fibrin glue. In vivo morphologic changes of AMs were evaluated using a spectral domain OCT equipped with an anterior segment imaging module (RTVue‐100, Optovue, Inc., Fremont, CA, USA). Anterior segment OCT examinations demonstrated morphologic changes, that is, re‐absorption of fibrin glue or subconjunctival hemorrhage, migration of epithelium, and integration of AM into sclera, of AMs over first postoperative months.ConclusionsAnterior segment OCT might provide additional structural information, including quantitative and qualitative data, on AMs after pterygium surgery as compared with conventional slit‐lamp examination.