Short wavelength automated perimetry and standard automated perimetry in central serous chorioretinopathy

Han Peng Zhou,Ryo Asaoka,Hiroshi Murata,Tatsuya Inoue,Shotaro Asano,Ryo Obata,Takumi Hara,Kazuaki Kadonosono,So Makino

doi:10.1038/s41598-020-73569-0

Han Peng Zhou, Ryo Asaoka + Show 7 more

Open Access

https://doi.org/10.1038/s41598-020-73569-0

Copy DOI

Abstract

Short wavelength automated perimetry (SWAP) is known for detecting the early reduction of retinal sensitivity (RS) in glaucoma. It’s application in retinal diseases have also been discussed previously. We investigated the difference in RS measured between standard white-on-white automated perimetry (WW) and blue-on-yellow SWAP in central serous chorioretinopathy (CSC). The overall RS (W-RS, S-RS) as well as the RS inside and outside of the serous retinal detachment (SRD) region were investigated in 26 eyes of 26 CSC patients using WW and SWAP. The central retinal thickness, central choroidal thickness, SRD area (SRDa), and SRD height at the fovea were measured using optic coherence tomography. RS inside the SRD region was lower than that of outside for both perimetries (both p < 0.001). The difference between RS inside and outside of the SRD region was greater in SWAP compared to WW (p < 0.001). Univariate analysis revealed significant correlations between SRDa and both W-RS and S-RS (both p < 0.001); moreover, multivariate analysis indicated that only S-RS was selected as the optimal model for SRDa. Our study demonstrated that SWAP was detected the decrease in RS more accurately than WW in CSC. These results may suggest the usefulness of SWAP for detecting change of retinal function in CSC.

Highlights

Short wavelength automated perimetry (SWAP) is known for detecting the early reduction of retinal sensitivity (RS) in glaucoma
SWAP is known for detecting reduction of retinal sensitivity (RS) in advance of standard automatic perimetry in glaucoma due to the sparse distribution of retinal ganglion cells which mediates blue stimuli[10,11,12,13,14,17,18,19,20,21,22], more recent studies have revealed the limited usefulness of this a pproach[23,24]
It was suggested that the difference of the retinal sensitivities within and outside the serous retinal detachment (SRD) region was significantly larger with SWAP than with white-on-white automated perimetry (WW) perimetry

Summary

Introduction

Short wavelength automated perimetry (SWAP) is known for detecting the early reduction of retinal sensitivity (RS) in glaucoma. We investigated the difference in RS measured between standard white-on-white automated perimetry (WW) and blue-on-yellow SWAP in central serous chorioretinopathy (CSC). The overall RS (W-RS, S-RS) as well as the RS inside and outside of the serous retinal detachment (SRD) region were investigated in 26 eyes of 26 CSC patients using WW and SWAP. SWAP is known for detecting reduction of retinal sensitivity (RS) in advance of standard automatic perimetry in glaucoma due to the sparse distribution of retinal ganglion cells which mediates blue stimuli[10,11,12,13,14,17,18,19,20,21,22], more recent studies have revealed the limited usefulness of this a pproach[23,24]. There is only limited number of studies which has shed light on this[25] and detailed examination has not been sufficiently performed

Methods

Results

Conclusion