Abstract
Short-Term Stability Study of Doxycycline Tablets by High Performance Liquid Chromatography, Spectrophotometry in the Ultraviolet Region and Turbidimetry
Highlights
Tetracyclines were first discovered around 1945 and were known to be produced from species of Streptomyces
Tetracyclines are bacteriostatic agents and out of several advantages, the broad-spectrum activity and low toxicity are the most important compared to other classes of antibiotics
The variability in the structures of this class of drug is responsible for the broad-spectrum activity, that is, this variability allows several interactions between the drugs and different molecules of the body [1,2]. This class of antibiotics is considered as a bacteriostatic agent because of its mechanism of action
Summary
Tetracyclines were first discovered around 1945 and were known to be produced from species of Streptomyces. Tetracyclines are bacteriostatic agents and out of several advantages, the broad-spectrum activity and low toxicity are the most important compared to other classes of antibiotics. The variability in the structures of this class of drug is responsible for the broad-spectrum activity, that is, this variability allows several interactions between the drugs and different molecules of the body [1,2]. This class of antibiotics is considered as a bacteriostatic agent because of its mechanism of action. The production of bacterial proteins does not occur [3]
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