Short-Term Intake of Yellowstripe Scad versus Salmon Did Not Induce Similar Effects on Lipid Profile and Inflammatory Markers among Healthy Overweight Adults despite Their Comparable EPA+DHA Content.

Wei Lin Chang,Sabariah Md Noor,Azrina Azlan,Su Peng Loh,Irmi Zarina Ismail

doi:10.3390/nu13103524

Wei Lin Chang, Sabariah Md Noor + Show 3 more

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https://doi.org/10.3390/nu13103524

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Journal: Nutrients	Publication Date: Oct 8, 2021
Citations: 2	License type: CC BY 4.0

Affiliation: Universiti Putra Malaysia, Airlangga University

Abstract

Yellowstripe scad (YSS) have comparable eicosapentaenoic acid and docosahexaenoic acid (EPA+DHA) content to salmon. We aimed to compare the effects of YSS and salmon on lipid profile and inflammatory markers. A randomized crossover trial with two diet periods was conducted among healthy overweight (with BMI 23.0–27.4 kg/m2) Malaysian adults aged 21–55 years. Steamed whole YSS fish (≈385 g whole fish/day) or salmon fillets (≈246 g fillet/day) were given for eight weeks (3 days per week), retaining approximately 1000 mg EPA+DHA per day. Diets were switched after an 8-week washout period. Fasting blood samples were collected before and after each diet period. A total of 49 subjects participated in the intervention (35% male and 65% female; mean age 29 (7) years). YSS did not induce any significant changes in outcome measures. However, the consumption of salmon as compared with YSS was associated with reduction in triglycerides (between-group difference: −0.09 mmol/1, p = 0.01), VLDL-cholesterol (between-group difference: −0.04 mmol/1, p = 0.01), atherogenic index of plasma (between-group difference: −0.05 mmol/1, p = 0.006), and IL-6 (between-group difference: −0.01 pg/mL, p = 0.03). Despite their comparable EPA+DHA content, short-term consumption of salmon but not YSS induced significant changes in lipid profile and inflammatory markers. Larger clinical trials are needed to confirm the findings.

Highlights

Introduction iationsMalaysia is among the world’s biggest consumers of fish, eating at least 56.5 kg of fish per person each year [1]
Researchers believe that the heart health benefit of fish is more promising in those fish rich in omega-3 fatty acids, which is attributed to the ability of fish to ameliorate hypertriglyceridemia [7,8] and resolve inflammatory processes [9]
We aimed to investigate the effects of consuming Yellowstripe scad (YSS) as compared with salmon on lipid profile and inflammatory markers among healthy overweight subjects

Summary

Introduction

Malaysia is among the world’s biggest consumers of fish, eating at least 56.5 kg of fish per person each year [1]. More than three quarters of Malaysians consume fish at least twice per week, eating 168 g of fish per day [2]. Eating fish on a regular basis can be beneficial for our health in many ways. Researchers believe that the heart health benefit of fish is more promising in those fish rich in omega-3 fatty acids, which is attributed to the ability of fish to ameliorate hypertriglyceridemia [7,8] and resolve inflammatory processes [9]. A recent meta-analysis demonstrated that consuming oily fish was associated with significant reductions in plasma triglycerides and an increase in HDL-cholesterol [10]. Omega-3 fatty acids reduce plasma lipid levels by inhibiting

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