Short term exposure to cigarette smoke on general activity and anxiety

Abstract

OBJECTIVE: Sidestream cigarette smoke differs from mainstream smoke because it presents more intense effects. We aimed to evaluate the performance of rats exposed to short term sidestream cigarette smoke during open field and elevated plus-maze tests. METHOD: Cigarette exposure was carried out during 5 days. The rats were exposed to the cigarette smoke during one hour. Elevated plus-maze and open field tests were applied according to previous studies. During the open field test we measured the time spent stopped, raising and the number of times that the rat intercepted each cross (locomotion). We examined the number of entries in the open and closed arms and the time spent in the closed and open arms during elevated plus-maze test. RESULTS: Control group presented significantly higher values regarding locomotion and raising during the open field test. No difference was noted between the groups regarding the elevated plus-maze test. CONCLUSION: Sidestream cigarette smoke exposure for short term on rats affects their performance during the open field test.