Abstract
The antiarrhythmic properties of n-3 polyunsaturated fatty acids (PUFAs) have been demonstrated in experimental models and in patients with coronary artery disease [1–6]. On the other hand, the signal-averaged electrocardiogram (SAECG) of the P waves has been used to predict the development of atrial fibrillation by measuring the filtered P wave duration (FPD) as an index of atrial conduction delay with high accuracy [7–10]. In this study, we assessed whether key long-chain n-3 PUFA, eicosapentaenoic acid (EPA) affected parameters of P wave SAECG in patients with coronary artery disease.
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