Abstract
The aim of this study was to assess the impact of exercise training on the quality of life (QoL) of patients diagnosed with stage IIIB and stage IV non–small cell lung cancer (NSCLC) compared to a passive control group (CG). The exercise-trained group (ETG) consisted of 18 patients, and the CG consisted of 8 patients. The training program in the ETG consisted of two 2-week running cycles interspersed with consecutive rounds of chemotherapy with cytostatic drugs. A comparison of the changes in the Short Form (36) Health Survey (SF-36), St. George’s Respiratory Questionnaire (SGRQ), and the Functional Assessment of Cancer Therapy-Lung (FACT-L) was the primary outcome. Analysis of the results of the SGRQ and the SF-36 questionnaire did not reveal any statistically significant differences in the assessment of QoL between the examined groups. The analysis of FACT-L questionnaires showed statistically significant changes, indicating deterioration of QoL in domains describing physical well-being in the CG. Therefore, the analysis of the results of the QoL assessment did not show any significant improvements in the group of patients undergoing comprehensive exercise training, although deterioration of QoL was noted in the CG.
Highlights
Cancer is currently the second leading cause of death and disability after cardiovascular disease, responsible for around 270,000 deaths annually in Europe [1]
The aim of this study was to evaluate the impact of in-hospital rehabilitation in patients diagnosed with stage IIIB and stage IV non–small cell lung cancer (NSCLC) who were disqualified from surgery and receiving regular chemotherapy
The study included 40 patients diagnosed with stage IIIB or stage IV NSCLC who were disqualified from surgery (Table 1)
Summary
Cancer is currently the second leading cause of death and disability after cardiovascular disease, responsible for around 270,000 deaths annually in Europe [1]. Morbidity and mortality statistics vary widely across the globe. About 16% of lung cancers are diagnosed during early stages; the 5-year survival rate is only 15% [2,3,4]. According to Global Cancer Observatory 2018 estimates, lung cancer is the most commonly diagnosed malignant neoplasm (2.1 million new cases, which corresponded to 11.6% of all cancer cases in 2018) [5]. Poland has some of the highest mortality and morbidity rates. Around 20,000 people die because of lung cancer.
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